Lisa Marsch, PhD
Center Director
Dr. Lisa A. Marsch is the Founding Director of the Dartmouth Center for Technology and Behavioral Health, a designated “Center of Excellence” supported by the National Institute on Drug Abuse at the National Institutes of Health.
She is also the Director of the Northeast Node of the National Drug Abuse Clinical Trials Network based out of Dartmouth and the Andrew G. Wallace Professor within the Departments of Psychiatry and Biomedical Data Science at the Geisel School of Medicine at Dartmouth College.
The Dartmouth Center for Technology and Behavioral Health (CTBH) is a national interdisciplinary Center housed at Dartmouth and includes affiliates within the Geisel School of Medicine, the College of Arts and Sciences, The Thayer School of Engineering, and the Dartmouth Institute for Health Policy and Clinical Practice. CTBH also includes interdisciplinary partners across the U.S. and internationally.
This Center uses science to inform the development, evaluation, and sustainable implementation of digital health tools (that leverage mobile, sensing and data analytics approaches) for behavior change targeting a wide array of populations and health behaviors. These tools are designed to deliver engaging and effective health monitoring and health behavior interventions and to collectively lead to transformations in the delivery of science-based health care.
In addition to directing this national Center, Dr. Marsch has been Principal Investigator on 40 grants, largely from the National Institutes of Health. She has led the development, evaluation and implementation of digital therapeutics for addiction treatment, HIV prevention, mental health, chronic pain management, substance abuse prevention, smoking cessation, and binge eating disorder. Her work in technology and addiction treatment has been particularly pioneering, as she is widely recognized as having led the development of one of the most widely tested and evidence-based mobile intervention for addiction treatment.
She additionally maintains a priority focus on mentoring investigators, including junior faculty as well as students and post-doctoral fellows.
Dr. Marsch publishes extensively and is a regular keynote speaker at national and international scientific meetings (including invited presentations at the White House, U.S. Congress, the World Bank, the US Surgeon General and the United Nations). She has served as a consultant to the Department of Mental Health and Substance Abuse at the World Health Organization and on the National Advisory Council to the National Institute on Drug Abuse at the National Institutes of Health. She serves on the Scientific Advisory Board of the Campus for Research Excellence and Technological Enterprise (CREATE) in Singapore.
Selected Publications
- Campbell CI, Chen CH, Adams SR, Asyyed A, Athale NR, Does MB, Hassanpour S, Hichborn E, Jackson-Morris M, Jacobson NC, Jones HK, Kotz D, Lambert-Harris CA, Li Z, McLeman B, Mishra V, Stanger C, Subramaniam G, Wu W, Zegers C, Marsch LA. Patient engagement in a multimodal digital phenotyping study of opioid use disorder. J Med Internet Res. 2023 Jun 13;25:e45556. doi: 10.2196/45556. PMID: 37310787.
- Jacobson N, Kowatsch T, Marsch, LA, editors. Digital therapeutics for mental health and addiction: The state of the science and vision for the future. 1st edition. Academic Press; 2022 September 27. Paperback ISBN: 9780323900454.
- Jacobson N, Quist RE, Lee CM, Marsch LA. Using digital therapeutics to target gaps and failures in traditional mental health and addiction treatments. In Jacobson N, Kowatsch T, Marsch LA, editors. Digital therapeutics for mental health and addiction: The state of the science and vision for the future. Academic Press; 2022 September 27. Chapter 2. Paperback ISBN: 9780323900454.
- Marsch LA, Chen CH, Adams SR, Asyyed A, Does MB, Hassanpour S, Hichborn E, Jackson-Morris M, Jacobson NC, Jones HK, Kotz D, Lambert-Harris CA, Li Z, McLeman B, Mishra V, Stanger C, Subramaniam G, Wu W, Campbell CI. The feasibility and utility of harnessing digital health to understand clinical trajectories in medication treatment for opioid use disorder: D-TECT study design and methodological considerations. Front Psychiatry. 2022 Apr 29;13:871916. doi: 10.3389/fpsyt.2022.871916. PMID: 35573377; PMCID: PMC9098973.
- Marsch LA. Digital health data-driven approaches to understand human behavior. Neuropsychopharmacology. 2021 Jan;46(1):191-196. doi: 10.1038/s41386-020-0761-5. PMID: 32653896; PMCID: PMC7359920.
- Cubillos L, Bartels SM, Torrey WC, Naslund J, Uribe-Restrepo JM, Gaviola C, Castro Díaz S, John DT, Williams MJ, Cepeda M, Gomez-Restrepo C, Marsch LA. The effectiveness and cost-effectiveness of integrating mental health services in primary care in low- and middle-income countries: A systematic review. BJPsych Bull. 2020 Apr 23:1-13. doi: 10.1192/bjb.2020.35. PMID: 32321610.
- Marsch LA. Digital health and addiction. Curr Opin Syst Biol. 2020 Apr;20:1-7. doi: 10.1016/j.coisb.2020.07.004. PMID: 32885099; PMCID: PMC7462117.
- Jalali A, Ryan DA, McCollister KE, Marsch LA, Schackman BR, Murphy SM. Economic evaluation in the National Drug Abuse Treatment Clinical Trials Network: Past, present, and future. J Subst Abuse Treat. 2020 Mar;112S:18-27. doi: 10.1016/j.jsat.2020.02.002. PMID: 32220406.
- Marsch LA, Campbell A, Campbell C, Chen CH, Ertin E, Ghitza U, Lambert-Harris C, Hassanpour S, Holtyn AF, Hser YI, Jacobs P, Klausner JD, Lemley S, Kotz D, Meier A, McLeman B, McNeely J, Mishra V, Mooney L, Nunes E, Stafylis C, Stanger C, Saunders EC, Subramaniam G, Young S. The application of digital health to the assessment and treatment of substance use disorders: The past, current, and future role of the National Drug Abuse Treatment Clinical Trials Network. J Subst Abuse Treat. 2020 Mar;112S:4-11. doi: 10.1016/j.jsat.2020.02.005. PMID: 32220409.
- Torrey WC, Cepeda M, Castro S, Bartels SM, Cubillos L, Suárez-Obando F, Camblor PM, Uribe-Restrepo JM, Williams M, Gómez-Restrepo C, Marsch LA. Implementing technology-supported depression and alcohol care in primary care in Colombia: Preliminary findings. Psychiatr Serv. 2020 Mar 10:appips201900457. doi: 10.1176/appi.ps.201900457. PMID: 32151216.
- Budney AJ, Marsch LA, Aklin WM, Borodovsky JT, Brunette MF, Campbell A, Dallery J, Kotz D, Knapp AA, Lord SE, Nunes EV, Scherer EA, Stanger C, Torrey WC. Workshop on the development and evaluation of digital therapeutics for health behavior change: Science, methods, and projects. JMIR Ment Health. 2020 Feb 26;7(2):e16751. doi: 10.2196/16751.PMID: 32130155.
- Moore SK, Grabinski M, Bessen S, Borodovsky JT, Marsch LA. Web-based prescription opioid abuse prevention for adolescents: Program development and formative evaluation. JMIR Formative Research. 2019 Jul 19;3(3):e12389. doi: 10.2196/12389. PMID: 31325289.
- Dallery J, Raiff BR, Grabinski MJ, Marsch LA. Technology-based contingency management in the treatment of substance use disorders. Perspect Behav Sci. 2019 Jul 9;42(3):445-464. doi: 10.1007/s40614-019-00214-1. eCollection 2019 Sep. PMID: 31976444.
- Holtyn AF, Bosworth E, Marsch LA, McLeman B, Meier A, Saunders EC, Ertin E, Ullah MA, Samiei SA, Hossain M, Kumar S, Preston KL, Vahabzadeh M, Shmueli-Blumberg D, Collins J, McCormack J, Ghitza UE. Towards detecting cocaine use using smartwatches in the NIDA clinical trials network: Design, rationale, and methodology. Contemp Clin Trials Commun. 2019 Jun 4;15:100392. doi: 10.1016/j.conctc.2019.100392. eCollection 2019 Sep. PMID: 31245651.
- Hassanpour S, Tomita N, Delise T, Crosier B, Marsch LA. Identifying substance use risk based on deep neural networks and Instagram social media data. Neuropsychopharmacology. 2018 Oct 24. doi: 10.1038/s41386-018-0247-x. PMID: 30356094.
- Borodovsky JT, Marsch LA, Budney AJ. Studying cannabis use behaviors with Facebook and web surveys: Methods and insights. JMIR Public Health Surveill. 2018 May 2;4(2):e48. doi: 10.2196/publichealth.9408. PMID: 29720366.
- Marsch LA. Opportunities and needs in digital phenotyping. Neuropsychopharmacology. 2018 Jul;43(8):1637-1638. doi: 10.1038/s41386-018-0051-7. PMID: 29703995; PMCID: PMC6006437.
- Guarino H, Fong C, Marsch LA, Acosta MC, Syckes C, Moore SK, Cruciani RA, Portenoy RK, Turk DC, Rosenblum A. Web-based cognitive behavior therapy for chronic pain patients with aberrant drug-related behavior: Outcomes from a randomized controlled trial. Pain Medicine. 2018;0:1–15. doi:10.1093/pm/pnx334.
- Eisenberg IW, Bissett PG, Canning JR, Dallery J, Enkavi AZ, Gabrieli SW, et al. Applying novel technologies and methods to inform the ontology of self-regulation. Behaviour Research and Therapy. 2017. PMID: 29066077.
- Naslund JA, Aschbrenner KA, Araya R, Marsch LA, Unützer J, Patel V, Bartels SJ. Digital technology for treating and preventing mental disorders in low-income and middle-income countries: a narrative review of the literature. Lancet Psychiatry. 2017 Jun;4(6):486-500. doi: 10.1016/S2215-0366(17)30096-2. PMID: 28433615.
- Naslund JA, Aschbrenner KA, Kim SJ, McHugo GJ, Unutzer J, Bartels SJ, Marsch LA. Health behavior models for informing digital technology interventions for individuals with mental illness. Psychiatr Rehabil J. 2017;40(3):325-35. PMID: 28182469; PMCID: PMC5550360.
- Marsch LA (Chair). Using technology-based therapeutic tools in behavioral health services. Treatment Improvement Protocol (TIP) Series 60. HHS Publication No. (SMA) 15-4924. Rockville, MD: Substance Abuse and Mental Health Services Administration, 2015.
- Marsch LA. Envisioning the future: transformation of health care systems via technology. In Marsch LA, Lord SE, Dallery J, editors. Behavioral health care and technology: Using science-based innovations to transform practice. New York: Oxford University Press; 2014.
- Marsch LA, Lord SE, Dallery J, editors. Behavioral health care and technology: Using science-based innovations to transform practice. New York: Oxford University Press; 2014.
- Marsch LA, Carroll KM, Kiluk BD. Technology-based interventions for the treatment and recovery management of substance use disorders: A JSAT special issue. Journal of Substance Abuse Treatment. 2014 Jan;46(1):1-4. PMID: 24041749; PMCID: PMC3825739.
- Marsch LA, Guarino H, Acosta M, Aponte-Melendez Y, Cleland C, Grabinski M,Brady R, Edwards J. Web-based behavioral treatment for substance use disorders as a partial replacement of standard methadone maintenance treatment. Journal of Substance Abuse Treatment. 2014 Jan;46(1):43-51. PMID: 24060350; PMCID: PMC3839618.
- Marsch LA. Leveraging technology to enhance addiction treatment and recovery. Journal of Addictive Diseases. 2012;31(3):313-8. PMID: 22873192.
- Marsch LA, Dallery J. Advances in the psychosocial treatment of addiction: the role of technology in the delivery of evidence-based psychosocial treatment. Psychiatric Clinics of North America. 2012; 35(2):481-93. PMID: 22640767.
- Marsch LA. Technology-based interventions targeting substance use disorders and related issues: An editorial. Subst Use Misuse. 2011;46(1):1-3. doi: 10.3109/10826084.2011.521037. PMID: 21190400.
- Bickel WK, Marsch LA, Buchhalter AR, Badger GJ. Computerized behavior therapy for opioid-dependent outpatients: a randomized controlled trial. Experimental and Clinical Psychopharmacology. 2008 Apr;16(2):132-43. PubMed PMID: 18489017 PMCID PMC2746734.
- Marsch LA, Bickel WK, Grabinski MJ. Application of interactive, computer technology to adolescent substance abuse prevention and treatment. Adolescent Medicine State of the Art Reviews. 2007 Aug;18(2):342-56, xii. Review. PubMed PMID: 18605650.
- Marsch LA, Bickel WK, Badger GJ, Stothart ME, Quesnel KJ, Stanger C, Brooklyn J. Comparison of pharmacological treatments for opioid-dependent adolescents: a randomized controlled trial. Archives of General Psychiatry. 2005 Oct;62(10):1157-64. PubMed PMID: 16203961.